Feasibility study on retinal vascular bypass surgery in isolated arterially perfused caprine eye model
نویسندگان
چکیده
منابع مشابه
Retinal function in an isolated, perfused mammalian eye.
Retinal function has been examined by identifying the activity of both rod and cone receptor systems in the electroretinogram (ERG) and the response of the optic nerve in the isolated cat eye, perfused through its ophthalmociliary artery with a solution devoid of hemoglobin. This preparation can maintain an ERG of normal configuration and of relatively large amplitude, dark-adapts after strong ...
متن کاملThe enucleated arterially perfused cat eye. I. Effects on protein permeability.
Protein permeability of the ciliary epithelium of enucleated arterially perfused cat eyes was studied. Tracer concentrations of 125I-albumin, in an arterial perfusate solution consisting of a balanced salt solution (BSS) without added colloid, was found in the anterior chamber fluid (AH) in a percentage similar to the AH/plasma ratio found for protein in the living cat eye. Stimulation of AH fo...
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INTRODUCTION Arteriosclerotic changes can lead to circulatory disturbances in various areas of the human vascular system. In addition to pharmacological therapy and the management of risk factors (e. g. hypertension, diabetes, lipid metabolism disorders, and lifestyle), surgical interventions also play an important role in the treatment of arteriosclerosis. Long-segment arterial occlusions, in ...
متن کاملThe Role of Anion Exchanger on Pulmonary Vascular Response to Sustained Alveolar Hypoxia in the Isolated Perfused Rabbit Lung
Background: Some respiratory diseases may induce alveolar hypoxia thereby hypoxic pulmonary vasoconstriction (HPV). However, the mechanisms of this physiologic phenomenon are not fully understood. This study was the first to investigate the role of anion exchanger in sustained HPV.Methods: Experiments were performed in the isolated perfused rabbit lung. After preparation, the lungs were divided...
متن کاملOcular ischemia and the effects of allopurinol on functional recovery in the retina of the arterially perfused cat eye.
PURPOSE This study sought to examine the acute effects of ocular ischemia and reperfusion on retinal function and determine the extent to which recovery during reperfusion is improved by allopurinol (AP), a blocker of xanthine oxidase (XO). The latter is presumed to be a major factor in the formation of free radicals associated with reperfusion of ischemic tissue. METHODS Electroretinographic...
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ژورنال
عنوان ژورنال: Eye
سال: 2011
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.2011.197